• RESEARCH HIGHLIGHT
  • 16 April 2026

Most of the individuals in a seventeenth-century-Switzerland burial site had performed strenuous manual labour and died before the age of 20.

Photo of a black and white engraving showing several people lowering plague victims' bodies into a pit from a cart, with a village skyline in the background

Bodies being interred during the Great Plague of London of 1665, in a mid-1800s interpretation by artist John Franklin. Credit: Hulton Archive/Getty

A plague outbreak fell hardest on low-income workers who could not afford to stay home even during an epidemic1. The disparities identified in human remains from the last plague outbreak recorded in Switzerland, in 1665–70, echo those seen during the COVID-19 pandemic.

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doi: https://doi.org/10.1038/d41586-026-01210-7

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